It is well known that skype and pulseaudio doesn't play well together. Skype's ALSA implementation doesn't really implement all of the standard ALSA API which caused alsa-plugins-pulse to not work with skype. Fortunately, as stated in PulseAudio Perfect Setup page, the skype static OSS (Open Sound System - another sound standard, different than ALSA) package can be used to work around this issue through padsp.
However, the skype_static-oss package come in a tarball, of which, is ugly/inconvenient to certain people (like me). So, I've hacked together a spec to repackage that binary blob and make Skype almost JustWorks for Fedora. I don't know what Skype's regulation for redistribution of their binaries, so, to be safe, I can only provide you the RPM spec file.
Here is the spec file : skype_static-oss.spec.
Just put the skype_static-oss tarball in your rpmbuild SOURCES directory, and invoke rpmbuild -bb with the spec file. Install the generated rpm and use it as you would normally.
For those who are not familiar with rpmbuild, heres a little script to get you going
# as root
yum install rpmdevtools
# as user
spectool -R -g -A skype_static-oss.spec
rpmbuild -bb skype_static-oss.spec
# ... wait ... wait ... wait
# grab the generated RPM
# rpm -ivh (the generated rpm)
Oh btw, the spec is under WTFPL. Just do wtf you want with it.